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5–4 μmol/L selection,[156][157] the focus of serotonin in synaptic vesicles was calculated at 270 mM.[182] pursuing vesicular launch, the ensuing concentration of serotonin from the synaptic cleft, to which serotonin receptors are exposed, is approximated to generally be about 300 μmol/L. So, while in vitro receptor binding affinities, effica